Living in Missouri 2001 Synopsis - Childhood pals grow up and fall apart at the seams in this dark comedy set in the Midwest. Ryan and Todd have been friends forever, but adulthood proves unfulfilling. Ryan's marriage to Amy is in jeopardy, while Todd lives with his parents and envies Ryan's marriage. When Amy begins confiding in Todd, he's convinced he's having an affair with his best friend's wife, resulting in a series of misunderstandings.